Lats2-Underexpressing Bone Marrow-Derived Mesenchymal Stem Cells Ameliorate LPS-Induced Acute Lung Injury in Mice
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چکیده
منابع مشابه
Bone marrow derived mesenchymal stem cells improve acute lung injury induced by sepsis in rats
Methods There were 25 rats in each group, including sepsis group, sepsis+antibiotic group, sepsis+antibiotic+MSCs group and sham group, twenty of which being sacrificed at 12 h, 18 h, 24 h and 48 h after surgery, respectively, five for survival analysis, and 5 normal controls. Survival rate, pulmonary physiological function, alveolar capillary barrier, lung inflammatory reaction and pathologica...
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Introduction: Mesenchymal stem cells (MSCs) are suitable candidates for the treatment of liver diseases. However, their low survival rate limits their efficacy following transplantation. This study aimed to evaluate the therapeutic potentials of H2O2-preconditioned umbilical cord-derived MSCs (UCMSCs) on acute liver failure (ALF) in mice. Methods: UCMSCs were pre-conditioned with different con...
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Objective(s): Allergic Asthma is an inflammatory disease of the lungs that is characterized by increased infiltration of leukocytes into the airways, limiting the respiratory function. Studies suggest that a defective general regulatory system against inflammation could be a significant factor in allergic asthma. It has been shown that Mesenchymal stem cells (MSCs) have a cellular immunosuppres...
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The present study determined the regenerative effect of bone marrow-derived stem cells (BMSCs) on thioacetamide (TA)-induced liver fibrosis in rats. A total of 30 male Wistar rats were randomly divided into sham control and treatment groups. The rats of the sham control group were subdivided into three groups and sampled on the 14th, 18th, and 20th weeks after fibrosis induction. The rats of th...
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ژورنال
عنوان ژورنال: Mediators of Inflammation
سال: 2019
ISSN: 0962-9351,1466-1861
DOI: 10.1155/2019/4851431